VISDB Viral Integration Site DataBase

VIS ID

TVIS10008313

Fusion event

HBV-PSMA3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|Polymerase|

Start

1611

Orient

-

Integrated sequence

CGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCAT| |GGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTC

Chromosome

chr14

Cytoband

q23.1

Reference genome

Start

End

58722083/58255365 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-346 ; hsa-mir-378a-3p ; hsa-mir-106b-5p ; hsa-mir-26a-5p ; hsa-mir-147a

Nearest miRNA

hsa-mir-208a/Upstream/3377172; hsa-mir-1185-1/Downstream/1391597;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/10186, chr14-CpG: 34/Downstream/42424

Upstream sequence

ttctagtatatacactgcacaacctcccaaatttggatgtggccactgtcatttcctgttccacactgatttttgcacagtacttactttttttcacagc

Downstream sequence

aaccactaacagccaagcttctcaaagatgtggtggcattgaaaggaatgtagtaaaacgatctaatgttcaaacggaactacttggaCATTTTTCTCCA