Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008324
Fusion event
HBV-CNTNAP4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
395
Orient
+
Integrated sequence
TGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTT| |TATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCC
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
Start
End
76328148/76294251 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/6263829; hsa-mir-11401/Downstream/574685;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/58956, chr16-CpG: 34/Downstream/340687
Upstream sequence
tcagggtggtgaggtacgatgataaatgtgtcgcaatccctgctattcagggacccacaagcaaatggagaagacaaaaagtaaCTCTAACAAAGAGCAG
Downstream sequence
ACTGTGATCCATACTACACTTCAGTATGGATTCCTGATCTAATACAATTCTGACTTATTTGGTAACCTGTGTGTTTCCTCTCATTTCTCTTAAAAATCAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.