ACSF3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008325
Fusion event
HBV-ACSF3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
1188
Orient
+
Integrated sequence
GCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTG| |CTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGC
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
89160458/89094050 (Hg38)
End
89160458/89094050 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACSF3
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-11401/Upstream/377713;
Nearest TSS
ENST00000527434/Upstream/146; ENST00000538340/Downstream/4661;
Nearest CpG islands
chr16-CpG: 106/Target, None/Upstream, None/Downstream
Upstream sequence
GTTGTGGCGAGGCAGATCCTGCCCCGTGGCCGCGGCCGTCTCGTAGGTgcgggcggcggggcccacgggaccgcggcggggtcggccgggcgcagagctc
Downstream sequence
tcgggggcgcgggctccggcgcccgccccTGGGTCGCAGCTGGGCTTGAGCCGTGGCCCGTGGCGCGGTCGCTTCCCCGCGAGCCGCCTGGGGCCGGGCG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate