VISDB Viral Integration Site DataBase

VIS ID

TVIS10008336

Fusion event

HBV-PLA2G4C integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2379

Orient

-

Integrated sequence

TCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGA| |ACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGG

Chromosome

chr19

Cytoband

q13.33

Reference genome

Start

End

48606219/48102962 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-132-3p ; hsa-mir-124-3p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-10395/Upstream/875941; hsa-let-7e/Downstream/906944;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/40895, chr19-CpG: 24/Downstream/34499

Upstream sequence

GGCAGGCGTTCCTGTGAAGGACCTCCTCACACACATCCTTTCCCAGTCTTCATCGTCCACACTTACAATGCTCAACAGCGGAGGAAACCAAGGCACAAAG

Downstream sequence

AAGTATGTCTGGGCTCGTAACAGCCCACAAAGGACAGCTCCAGGAACTAACCCAAAGCTGTTGAAATATAAGGCTTTCGTTGTtgttgtttgtagagatg