Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008337
Fusion event
HBV-LAIR2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2702
Orient
-
Integrated sequence
CTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTT| |ATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAG
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
Start
End
55013368/54502152 (Hg38)
Orient
-
Location type
upstream
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7e/Upstream/219972; hsa-mir-10394/Downstream/143157;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/30476, chr19-CpG: 25/Downstream/24872
Upstream sequence
cttggtctctgcctctgcgtcgcttggcgtgatgtcctcaggtttcgtccgtgttgtcgcccatggcagaattttcttccttgtttaaggctgaatagta
Downstream sequence
ttcccctgtgtgtgcaccacattttctatatcaattcttctatcaatggacatttagatgattttcacgtcttagctattgcgaatagtgctgcagtgat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.