Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008355
Fusion event
HBV-ATP2C1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
1139
Orient
+
Integrated sequence
TGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTG| |AACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGC
Host Sequence
Chromosome
chr3
Cytoband
q22.1
Reference genome
End
130651061/130932217 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7g/Upstream/1659974; hsa-mir-1224/Downstream/1053638;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/37576, chr3-CpG: 40/Downstream/94327
Upstream sequence
caggTGTGGCTGATGGctctggctttggctgcctgacgtttcctggatcctgcagcgtggcacaggacacatttgcctcctggttgccttctggacttgc
Downstream sequence
ATACTGTTTATGGAGAAAGGAAATAATTTTTAGATGTTTTTTACCTAAAATTTTTCATTTGTTGGGGCTTACTGTTAGGTTGGAATTCCTGTATTTTTAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.