VISDB Viral Integration Site DataBase

VIS ID

TVIS10008374

Fusion event

HBV-KIAA1211 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1806

Orient

-

Integrated sequence

ACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGC| |ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG

Chromosome

chr4

Cytoband

q12

Reference genome

Start

End

56985044/56118878 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-769-5p ; hsa-mir-27b-3p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-4635 ; hsa-mir-4729 ; hsa-mir-664a-3p ; hsa-mir-1264

Nearest miRNA

hsa-mir-12113/Upstream/3406131; hsa-mir-1243/Downstream/4803741;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/69143, chr4-CpG: 137/Downstream/195181

Nearby gene

CEP135(-85515) ; KIAA1211(+51317) ;

Upstream sequence

acagctcccaaagtgattccactgcaggtggtgccacaagccacattttggtagACGGCAGGTTTCAGAGGACGGACACGTGGCATCCTGTTGACATAGG

Downstream sequence

ACATATAATCAGAGAAAGTGTTCCATCTATATTTTACAGTGGATAATTTTTTACTTACATCAACAAAATACTCCTTATATGGGCCATCCATTGAGACATG