Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008403
Fusion event
HBV-FLJ34503 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
526
Orient
-
Integrated sequence
CTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCT| |GCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGC
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
End
114229335/113908171 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/7123951; hsa-mir-1202/Downstream/5160876;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/47660, chr6-CpG: 128/Downstream/62076
Upstream sequence
TCTACTTCACTTCATACTatattccccttagcaacattgaatccttaagacatccgttaaaagtcaggagcattcagttaacagcttaatagggttggga
Downstream sequence
TTCCTCTCTGGTTTCCAAGCAAGTAGGCATGCTTTAAGGAAGTTGGCCATAGAGGTGATATAAGACATGCTCATAAGCAACTATAAAATAAAGCAGTAAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.