Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008417
Fusion event
HBV-FBXO16 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2018
Orient
+
Integrated sequence
ATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCG| |GGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTG
Host Sequence
Chromosome
chr8
Cytoband
p21.1
Reference genome
Start
End
28326656/28469139 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-124-1/Upstream/583023; hsa-mir-10400/Downstream/35977;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/56666, chr8-CpG: 115/Downstream/24800
Upstream sequence
gagaaaccccgtctctactaaaaatacaaaattagccaggcgtggtggcgcatgcctgtaatcccagctactcgagaggctgaggcaggagaatcgctgg
Downstream sequence
ctctactaaaaaaaaattacaaaattagctgggcatggtggcacatgcctgtaatcccagctactcgggaggctgaaggaggagaatggcttgaacctgg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.