VISDB Viral Integration Site DataBase

VIS ID

TVIS10008421

Fusion event

HBV-SLC44A1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1837

Orient

+

Integrated sequence

GGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCC| |TAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTAC

Chromosome

chr9

Cytoband

q31.1

Reference genome

Start

End

108151714/105389433 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-122-5p ; hsa-mir-19b-3p ; hsa-mir-545-5p ; hsa-mir-7161-3p ; hsa-mir-3156-5p ; hsa-mir-3185 ; hsa-mir-203a-3p ; hsa-mir-3646 ; hsa-mir-3941 ; hsa-mir-6865-3p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-1197 ; hsa-mir-875-5p ; hsa-mir-4684-5p ; hsa-mir-4668-5p ; hsa-mir-1283 ; hsa-mir-3675-3p ; hsa-mir-4311 ; hsa-mir-6809-5p ; hsa-mir-5695 ; hsa-mir-6830-5p ; hsa-mir-651-3p ; hsa-mir-2681-5p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-let-7a-2-3p ; hsa-let-7c-3p ; hsa-let-7g-3p ; hsa-mir-129-5p ; hsa-mir-4797-5p ; hsa-mir-493-5p

Nearest miRNA

hsa-let-7a-1/Upstream/7160216; hsa-mir-12126/Downstream/1211495;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/143793, chr9-CpG: 73/Downstream/58371

Upstream sequence

ctgactgtgaaccagaggctggacttttctcctagaagcctctctctagtcctcctgtgtagttcctgcatttcagagcaggcaatccgcaaaatcccac

Downstream sequence

GTCTAAAGTTTATTCAGGGGTAATTTCCCTGATGTCTGTATAAAATCAAGATCTTATTTTACTGATGCATAAGTCCTAGTGGGTCAAGACTAGGCATATG