VISDB Viral Integration Site DataBase

VIS ID

TVIS10008422

Fusion event

HBV-FSD1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1135

Orient

-

Integrated sequence

AATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATA| |CCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGC

Chromosome

chr9

Cytoband

q31.2

Reference genome

Start

End

108258749/105496468 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-4786-3p ; hsa-mir-501-5p ; hsa-mir-500a-5p ; hsa-mir-4668-3p ; hsa-mir-1305 ; hsa-mir-380-3p ; hsa-mir-411-3p ; hsa-mir-379-3p ; hsa-mir-4495 ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-130a-5p ; hsa-mir-136-5p ; hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-23c ; hsa-mir-3145-5p ; hsa-mir-508-5p

Nearest miRNA

hsa-let-7a-1/Upstream/7267251; hsa-mir-12126/Downstream/1104460;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/47996, chr9-CpG: 31/Downstream/61496

Upstream sequence

ttttggaataggtgtggtgtggtgttgaaaaaaatgtgtattctgttgatttggggtggagagttctgtagatgtctattatgtctgcttggtgcagagc

Downstream sequence

taggtcaaattgggaagaactgacatcttaagaacattgagtatttctatccataaacattggaatgtctctacattgatttagttctttgatttctttc