VISDB Viral Integration Site DataBase

VIS ID

TVIS10008424

Fusion event

HBV-NFX1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2941

Orient

-

Integrated sequence

TCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGA| |TTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTG

Chromosome

chr9

Cytoband

p13.3

Reference genome

Start

End

33299172/33299174 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-541-5p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-8057 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-143-5p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4284 ; hsa-mir-24-3p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-367-5p ; hsa-mir-1267

Nearest miRNA

hsa-mir-101-2/Upstream/190409; hsa-let-7a-1/Downstream/168695;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/8169, chr9-CpG: 41/Downstream/148274

Upstream sequence

TGGAAATCTGAAATCCTTCTGATCAGAGCATTCACAACAGTAGCAGAGCGAGTTATTCTGATGCGGAGGTCAGTCTACTTCAGTGCTGGGGAAATAACTG

Downstream sequence

agaaattagcactggtataatcatattaactaaactacagatgttattcagatttcaccagtttttctgccaatgtcctttttctgtttgaggacccaat