VISDB Viral Integration Site DataBase

VIS ID

TVIS10008426

Fusion event

HBV-LONRF3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|middle S protein|

Start

125

Orient

+

Integrated sequence

TGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAAT| |CTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACA

Chromosome

chrX

Cytoband

q24

Reference genome

Start

End

118140820/119006857 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-5704 ; hsa-mir-3926 ; hsa-mir-645 ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-605-5p ; hsa-mir-6883-5p ; hsa-mir-4728-5p ; hsa-mir-6785-5p ; hsa-mir-149-3p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-3202 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-7515 ; hsa-mir-1252-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-5584-5p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-4311 ; hsa-mir-6758-5p ; hsa-mir-3941 ; hsa-mir-4789-5p ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-4652-3p ; hsa-mir-106a-3p ; hsa-mir-4795-3p ; hsa-mir-3182 ; hsa-mir-1237-3p ; hsa-mir-5088-3p ; hsa-mir-6756-3p ; hsa-mir-4699-3p ; hsa-mir-3127-3p ; hsa-mir-656-3p ; hsa-mir-4662a-3p ; hsa-mir-137 ; hsa-mir-25-3p ; hsa-mir-92b-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-8485 ; hsa-mir-433-3p ; hsa-mir-4704-3p ; hsa-mir-4463 ; hsa-mir-4524b-3p ; hsa-mir-4637 ; hsa-mir-5583-5p ; hsa-mir-3129-3p ; hsa-mir-5692a ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-499b-5p ; hsa-mir-4494 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-126-5p

Nearest miRNA

hsa-let-7f-2/Upstream/620386; hsa-mir-105-1/Downstream/639881;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/30261, chrX-CpG: 25/Downstream/66687

Upstream sequence

taacattatttttcatacagaaaattcaaaaaagggtacaaaaaagctgtataaactaataaacaagtttataagttcccatgatacaaggtcaatatat

Downstream sequence

gattacaggcgtgagccaccacgcccggcctaatttttgtatttttagtagaaatggggtttcaccatattggtcaggctggtctcgaactcctgacctc