VISDB Viral Integration Site DataBase

VIS ID

TVIS10008444

Fusion event

HBV-ETNK2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1640

Orient

+

Integrated sequence

CGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATAT| |TGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGA

Chromosome

chr1

Cytoband

q32.1

Reference genome

Start

End

204114513/204145385 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-142-3p ; hsa-mir-132-3p ; hsa-mir-125a-5p ; hsa-mir-155-5p ; hsa-let-7c-5p

Nearest miRNA

hsa-mir-101-1/Upstream/2142149; hsa-mir-1182/Downstream/1302917;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/70003, chr1-CpG: 97/Downstream/5885

Upstream sequence

AGGTCACACAGTGACAGCACAGTCAAAGGAAGCTGCAGTATCAAGGATTATGTctgagcaccagaagcctggctctagttgctaagctgccactgatcag

Downstream sequence

cgaccttgggcaggttccatcccctccctgggcctcggttttccacttgtcaaataacagctgtgggctgaaaggttggaaggacctgttctctacaaac