Basic Information
VIS ID
TVIS10008445
Fusion event
HBV-LOC105372922 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|
Start
1843
Orient
-
Integrated sequence
GGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCA| |TCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGA
Host Sequence
Chromosome
chr1
Cytoband
q41
Reference genome
GRCh37/hg19
Start
218174144/218000802 (Hg38)
End
218174144/218000802 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105372922
Nearest miRNA
hsa-mir-101-1/Upstream/5923117; hsa-mir-1182/Downstream/2117051;
Nearest TSS
ENST00000473358/Upstream/107902; ENST00000420347/Downstream/31033;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/369667, chr1-CpG: 120/Downstream/163636
Nearby gene
LINC00210(-79998) ; RRP15(+284485) ;
Upstream sequence
gcgacattccatactgatccccacctcacttgtacatagttctcttctccactttttataacaccatattcttttcctcctagctctgtaactgtttttt
Downstream sequence
tggtcttttctagctcatcctcatctaaattaaatgttagaatggtccaatcaaagtttggcatatgttctcttttattctcagtctaattctccgttta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate