VISDB Viral Integration Site DataBase

VIS ID

TVIS10008451

Fusion event

HBV-RYR3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1827

Orient

-

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT

Chromosome

chr15

Cytoband

q14

Reference genome

Start

End

33856439/33564238 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-367-5p

Nearest miRNA

hsa-mir-1268a/Upstream/2499097; hsa-mir-10393/Downstream/817831;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/252436, chr15-CpG: 114/Downstream/474130

Upstream sequence

CAGTTGTGCTAAAGAGTCAGATTGGACATAGGTTCAGCCAGGGCTTCTGGGACTCGAGGTGCCAAGAGTCCAGAGTAGAGAGAACTGCAAAAACATGAGC

Downstream sequence

CTAAAATTCTACATGCCGTTTCCTCTAGAATCCTAAGCTGACCGTGGATGGGGTGTGAAGCCAAAATAGTaaagcgaaactgctgtgataatgaagagca