VISDB Viral Integration Site DataBase

VIS ID

TVIS10008456

Fusion event

HBV-ZRANB3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

958

Orient

+

Integrated sequence

GGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACT| |TCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATG

Chromosome

chr2

Cytoband

q21.3

Reference genome

Start

End

136005058/135247488 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

FRA2S ; FRA2F

Target gene

miRNAs that regulate target gene

hsa-mir-6855-5p ; hsa-mir-5096 ; hsa-mir-3170 ; hsa-mir-4662a-5p ; hsa-mir-193b-5p ; hsa-mir-6890-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p

Nearest miRNA

hsa-mir-1285-2/Upstream/389615; hsa-mir-10b/Downstream/417909;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/194800, chr2-CpG: 36/Downstream/283912

Upstream sequence

TCCCATACAGCTGAATAAAATACTGACAATATCCACTCTTAGGCACAACTACTAGTGTTTCTCTGCAGATAGAGAGAAAACAAAACAAAACACACAAAAT

Downstream sequence

AAAACACATTTTGATTTTTTTTAAAACCCAAAGTAGTAAAAAAGAAAACGTTATTACTTATTATTATTTTTTTTTAGAGACATGGTCTTAGCCAGGTGCA