Fusion event
HBV-chr4 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
AAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCA| |GTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAG
End
49114434/49112417 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/1459674; hsa-mir-1243/Downstream/3600265;
Upstream sequence
GCAGTTGATTAAATCTGGGTTTTATCGAGGGTGCCCATGTGTCCCAATTCTGGTTCGCATATAGGTATAAGtaaaatgattatataattaattgttggaa
Downstream sequence
ttccattccattccattccattccattccattccattccattccattccactccattaaattccactccactccggttgattccattccatttcattcca
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.