Basic Information
VIS ID
TVIS10008460
Fusion event
HBV-chr4 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
676
Orient
-
Integrated sequence
AAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCA| |GTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAG
Host Sequence
Chromosome
chr4
Cytoband
p11
Reference genome
End
49114434/49112417 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/1459674; hsa-mir-1243/Downstream/3600265;
Nearby gene
CWH43(-50339) ;
Upstream sequence
GCAGTTGATTAAATCTGGGTTTTATCGAGGGTGCCCATGTGTCCCAATTCTGGTTCGCATATAGGTATAAGtaaaatgattatataattaattgttggaa
Downstream sequence
ttccattccattccattccattccattccattccattccattccattccactccattaaattccactccactccggttgattccattccatttcattcca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate