Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008480
Fusion event
HBV-DDX11L2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
383
Orient
+
Integrated sequence
GGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTG| |TCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTA
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
End
114360987/113603410 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/20314; hsa-mir-10b/Downstream/117880;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/18689, chr2-CpG: 61/Downstream/23602
Upstream sequence
taacccctaaccctaacccctaaccctaaccctaccccaaccccaaacccaaccctaacccaaccctaacccctaaccctaacccctaccctaaccccta
Downstream sequence
gccctagccctagccctaaccctaaccctcgccctaaccctcaccctaaccctcaccctcaccctaacccaacgtctgtgctgagaagaatgctgctccg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.