Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008491
Fusion event
HBV-IL1RAPL2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|middle S protein|
Start
118
Orient
+
Integrated sequence
CAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTAT| |CGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTT
Host Sequence
Chromosome
chrX
Cytoband
q22.3
Reference genome
End
104182110/104937429 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7f-2/Upstream/9874203; hsa-mir-105-1/Downstream/1702385;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/370067, chrX-CpG: 62/Downstream/884912
Upstream sequence
tgggacaacaggcacccgccaccacgcccggctaattttttgtatttttagtagagacagggtttcaccgtgttagccaggatggtcttgatctcctcac
Downstream sequence
ggatggaaaaggagagagtggagaagacatacccagttactacaaactcccatttgaaagtgatacccatcacttctgttcacattccattggcaagaat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.