PPP2R5C _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008502
Fusion event
HBV-PPP2R5C integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1755
Orient
-
Integrated sequence
ATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGAT| |TAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCAT
Host Sequence
Chromosome
chr14
Cytoband
q32.31
Reference genome
End
102385212/101918875 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1185-1/Upstream/358453; hsa-mir-12121/Downstream/620769;
Nearest cancer related gene
PPP2R5C(TSG, No orient, 0)
Upstream sequence
TCCTGCCTGGGTTCAAGGAGCGTTTCAGCTGCCGTGTTTCCCTGAGCGTCCCTCCCTGTTTCAAATGCCTGTAAACTAAAACAGTAGTCCCAAATGGCCT
Downstream sequence
GGGGACATTGGCCTTTCTCACTGAGAAACTTTAACCTCTTTTTGACCAGCGAAAGAATTCCAAAAGACATCCCCTTCTAAAATTCTGAGGTAAGAAGTGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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