VISDB Viral Integration Site DataBase

VIS ID

TVIS10008504

Fusion event

HBV-RAD51B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1761

Orient

-

Integrated sequence

GGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTT| |AAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTA

Chromosome

chr14

Cytoband

q24.1

Reference genome

Start

End

68362393/67895676 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-484 ; hsa-mir-4668-5p ; hsa-mir-2053 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-30b-3p ; hsa-mir-3689a-3p ; hsa-mir-1273h-5p ; hsa-mir-569 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-766-5p ; hsa-mir-6871-5p ; hsa-mir-4496 ; hsa-mir-4506

Nearest miRNA

hsa-mir-208a/Upstream/453746; hsa-mir-1185-1/Downstream/4621144;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/220511, chr14-CpG: 40/Downstream/732622

Upstream sequence

Gccactagactataagcagtatgggggcagagaaactatttgttttgtccacagttgtatcctttgaagctaggacaatgtatggcacataatatatgct

Downstream sequence

ctaattaatatttattgaatgattaagtCTTAGTTTAGGATATGATATAATATTTAAAGTTCTCTTCCTTCTGGCTCCAACCTACTCCTCCCATGTTGTC