VISDB Viral Integration Site DataBase

VIS ID

TVIS10008505

Fusion event

HBV-RAD51B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1828

Orient

+

Integrated sequence

AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT

Chromosome

chr14

Cytoband

q24.1

Reference genome

Start

End

68362448/67895731 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-484 ; hsa-mir-4668-5p ; hsa-mir-2053 ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-30b-3p ; hsa-mir-3689a-3p ; hsa-mir-1273h-5p ; hsa-mir-569 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-766-5p ; hsa-mir-6871-5p ; hsa-mir-4496 ; hsa-mir-4506

Nearest miRNA

hsa-mir-208a/Upstream/453801; hsa-mir-1185-1/Downstream/4621089;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/220566, chr14-CpG: 40/Downstream/732567

Upstream sequence

tgtatcctttgaagctaggacaatgtatggcacataatatatgctctaattaatatttattgaatgattaagtCTTAGTTTAGGATATGATATAATATTT

Downstream sequence

AAAGTTCTCTTCCTTCTGGCTCCAACCTACTCCTCCCATGTTGTCATTTCTCTTCTGTGCAGGCTGCTGGTATACTACCCCGAGACCTCTCTATGGCTTT