TMEM87A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008506
Fusion event
HBV-TMEM87A integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1847
Orient
+
Integrated sequence
GAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTC| |TTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTA
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
End
42564783/42272585 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-1233-1/Upstream/72919; hsa-mir-10393/Downstream/1521074;
Upstream sequence
GCAGAGCAGAATGAAACAAAAAGGCCAACGTAGGTTTAATGGGGCTAATGCTTTTCAGCATTTCCTCCCTGCATCTGGTTTTTGTCTGCTCACAGGACTA
Downstream sequence
TACCTGTTACTGAAATAAGGTTTAAAATGGGTAAGGGGCAGAAAGGGTCAACCCATGTAGTTAATTATCCAAATGAAAGACTAGCCTTACCACATTAAAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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