Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008516
Fusion event
HBV-ASB18 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
613
Orient
-
Integrated sequence
CCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCC| |CATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCT
Host Sequence
Chromosome
chr2
Cytoband
q37.2
Reference genome
End
237167091/236258448 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10b/Upstream/3707875; hsa-mir-149/Downstream/1252483;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/20515, chr2-CpG: 33/Downstream/248999
Upstream sequence
aaatgaggaaattaaggttcaaagaggtggtctgacatgttcaaggtcacacaggtcacgggagagcttaggcaagaaactgggtccccttcctctcagt
Downstream sequence
cccttgcccttcccattacaccacATCTTGGCACCATCATCAATGGGTACGCTCTTGTCACTGTGTTGGAAAATGATTCCTCTAAGGCGGGAGCTGTGCT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.