VISDB Viral Integration Site DataBase

VIS ID

TVIS10008526

Fusion event

HBV-CPNE4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1760

Orient

-

Integrated sequence

AGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGT| |TAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCT

Chromosome

chr3

Cytoband

q22.1

Reference genome

Start

End

131868642/132149798 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-148b-3p ; hsa-mir-122-5p

Nearest miRNA

hsa-let-7g/Upstream/163867; hsa-mir-1224/Downstream/2218006;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/114503, chr3-CpG: 57/Downstream/267331

Nearby gene

CPNE4(-114798) ; ACPP(+167569) ;

Upstream sequence

TTCTTCCCCCAAAATCACTGCCCATGCATCCCAAATTTATACCAATCAGTTCTCAGATTAACTAGGAAACCAGAGGGTATAGACCACACAGAAAGGCCTT

Downstream sequence

gtgaaaggtctcattcccccacatgctggaagtgctattagcctcttagagggaatgcctgggctgaagagagtcaccttgcccaaggccacaccccctt