VISDB Viral Integration Site DataBase

VIS ID

TVIS10008527

Fusion event

HBV-CLSTN2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1829

Orient

+

Integrated sequence

GACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCA| |CCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTT

Chromosome

chr3

Cytoband

q23

Reference genome

Start

End

139701621/139982779 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-3180-5p ; hsa-mir-3607-3p ; hsa-mir-5195-3p ; hsa-mir-145-5p ; hsa-mir-10b-3p ; hsa-mir-1343-5p ; hsa-mir-145-3p ; hsa-mir-1914-5p ; hsa-mir-3150a-3p ; hsa-mir-3175 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-5703 ; hsa-mir-6763-5p ; hsa-mir-6825-5p ; hsa-mir-6878-5p ; hsa-mir-7152-5p ; hsa-mir-939-5p

Nearest miRNA

hsa-let-7g/Upstream/5544873; hsa-mir-1224/Downstream/11583097;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/46506, chr3-CpG: 37/Downstream/699838

Upstream sequence

TCCATAACAGTTTAAAACTAACTCTAGAATGATGCTCCATTTCTTCATGCTCTCCCCAATGCCTCCCCATTACAAGATGTGTTTTCACAGCTACAGTAGA

Downstream sequence

GACTCAATAAAACTAGACATGTCTAGATAATATTGAGATAAGTTGGAAATGTTGATAGTGGACCAATTCTAGACATTAGTTCAGACTATATATAGAGAGA