VISDB Viral Integration Site DataBase

VIS ID

TVIS10008531

Fusion event

HBV-HNF4G integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1809

Orient

+

Integrated sequence

TCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACC| |AGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACA

Chromosome

chr8

Cytoband

q21.13

Reference genome

Start

End

76337372/75425137 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-129-5p ; hsa-mir-3149 ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-4799-5p ; hsa-mir-30a-5p ; hsa-mir-194-5p ; hsa-mir-34a-5p

Nearest miRNA

hsa-mir-124-1/Upstream/719390; hsa-mir-10400/Downstream/1541631;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/16948, chr8-CpG: 59/Downstream/1256883

Nearby gene

CRISPLD1(-390579) ; HNF4G(+114831) ;

Upstream sequence

CGCCAACCTCAGTTCCTCCTCTGACTGCCTCTCTCCATCTGTATTGCAAAACACCAAACTCTCTGCCAAAGAACACATGTAAGTGACCAAAACAGCAAGA

Downstream sequence

tgcagtggtgcaatctcggctcactgcaactttgtctcctaggttcaagtgattctcccgtctcagcctcccgagtagctgggattacaggcacctgcca