VISDB Viral Integration Site DataBase

VIS ID

TVIS10008543

Fusion event

HBV-ARL3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2216

Orient

-

Integrated sequence

TGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACAT| |TTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCT

Chromosome

chr10

Cytoband

q24.32

Reference genome

Start

End

104474006/102714249 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-6875-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-103a-2-5p ; hsa-mir-4680-5p ; hsa-mir-4778-3p ; hsa-mir-877-3p ; hsa-mir-512-5p ; hsa-mir-3646 ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a ; hsa-mir-4660 ; hsa-mir-1976 ; hsa-mir-6736-3p

Nearest miRNA

hsa-mir-107/Upstream/277665; hsa-mir-1307/Downstream/680004;

Nearest TSS

Nearest CpG islands

chr10-CpG: 94/Target, None/Upstream, None/Downstream

Upstream sequence

AGATAGCAGGCTGAGCGACGTCCCATTCCCTCCTTGGCTTTAAGCGCAGTGCTCCGCCCTGGGCCTGGGGACGGGAGGGGGATAACCGGCCGGCTCCAAG

Downstream sequence

GGGGCCCAGGCCCCCACACTCACCATCCTCCCGCCGAGTCcctcctcctcctcctcctcctgctgcctcccccGTTACCAGGGGCAACTGCTGCGGCGCC