ANKS1B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008547
Fusion event
HBV-ANKS1B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2713
Orient
+
Integrated sequence
TGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAA| |CATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTT
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
99865209/99471431 (Hg38)
End
99865209/99471431 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKS1B
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-let-7i/Upstream/1475983; hsa-mir-1178/Downstream/718453;
Nearest TSS
ENST00000382841/Upstream/85134; ENST00000324341/Downstream/176322;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/575835, chr12-CpG: 85/Downstream/513034
Upstream sequence
GAGTCCAAAAGTACCTAGTTATTATAACTTTGGAAGCCCAGAGTCCTGTTTAAAAAAAAAATTAGATGTCACAAAAGGCCTCTGAGCTCTTGATGAATGT
Downstream sequence
GTTATAAGTTTTGTGTACATCTTAAGGGACCTCTTTCACAAGCAACCAGAAGTCCTTTTGTAATTACTTATGCTCAACATCTATTTCTAATTTGCAGAGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate