ANKS1B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008548
Fusion event
HBV-ANKS1B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1816
Orient
-
Integrated sequence
CTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCA| |TGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
99865220/99471442 (Hg38)
End
99865220/99471442 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANKS1B
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-let-7i/Upstream/1475994; hsa-mir-1178/Downstream/718442;
Nearest TSS
ENST00000382841/Upstream/85145; ENST00000324341/Downstream/176311;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/575846, chr12-CpG: 85/Downstream/513023
Upstream sequence
TACCTAGTTATTATAACTTTGGAAGCCCAGAGTCCTGTTTAAAAAAAAAATTAGATGTCACAAAAGGCCTCTGAGCTCTTGATGAATGTGTTATAAGTTT
Downstream sequence
TGTGTACATCTTAAGGGACCTCTTTCACAAGCAACCAGAAGTCCTTTTGTAATTACTTATGCTCAACATCTATTTCTAATTTGCAGAGCTATGATGAGGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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