VISDB Viral Integration Site DataBase

VIS ID

TVIS10008551

Fusion event

HBV-PSMD11 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1775

Orient

-

Integrated sequence

TCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTAC| |TAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCC

Chromosome

chr17

Cytoband

q11.2

Reference genome

Start

End

30770665/32443647 (Hg38)

Orient

+

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-16-5p ; hsa-mir-1236-3p ; hsa-mir-940 ; hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-744-5p ; hsa-mir-324-5p ; hsa-mir-320a ; hsa-mir-10b-5p ; hsa-mir-93-5p ; hsa-mir-92a-3p ; hsa-mir-142-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-8085 ; hsa-mir-6878-5p ; hsa-mir-6731-5p ; hsa-mir-765 ; hsa-mir-4745-5p ; hsa-mir-4481 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6760-5p ; hsa-mir-4433b-3p ; hsa-mir-6888-5p ; hsa-mir-6873-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-873-5p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-1253 ; hsa-mir-4768-3p ; hsa-mir-4688 ; hsa-mir-6743-5p ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-6515-5p ; hsa-mir-4728-5p ; hsa-mir-766-5p ; hsa-mir-605-3p ; hsa-mir-4308 ; hsa-mir-4254 ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-744-3p ; hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-449b-3p

Nearest miRNA

hsa-mir-1180/Upstream/93445; hsa-mir-10226/Downstream/4590098;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/93206, chr17-CpG: 94/Downstream/295

Upstream sequence

GCCTCCTTTTATGGgacagcacattccatttttggatcgtcatcacctagagaaaggtcttccttaatactgaattgtctttgtatccttttagcacctt

Downstream sequence

tcttaagtttaaccctaagtggtctcatagaatgtcatttttccgtccacacgacgtcttcactgatatctgTGACTTTAGTTGAAGGGGCTGAAGATAT