Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008558
Fusion event
HBV-TMEM232 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2542
Orient
-
Integrated sequence
TCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCT| |TTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGC
Host Sequence
Chromosome
chr5
Cytoband
q22.1
Reference genome
End
109990401/110654700 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/140785; hsa-mir-103a-1/Downstream/5601043;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/769202, chr5-CpG: 60/Downstream/84204
Upstream sequence
AGGAAACGCCTCCCGGCATTCAATGAAGATCGCTGATACCCAGAAGACACCCCAGTATTATGGGTGCAGTTAGTGTGTCTTTGAAAAGCTGATGATGTCT
Downstream sequence
agatggggatggcattgaatctataaattaccttgggcagtatggccattttcacgatattgattcttcctacccatgagcatggaatgttcttccattt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.