Basic Information
VIS ID
TVIS10008572
Fusion event
HBV-chr7 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2075
Orient
-
Integrated sequence
CTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGC| |AATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACT
Host Sequence
Chromosome
chr7
Cytoband
p21.2
Reference genome
End
13757300/13717675 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-339/Upstream/6650630; hsa-mir-10399/Downstream/4409545;
Nearby gene
ARL4A(-1026742) ; ETV1(+173556) ;
Nearest cancer related gene
ETV1(OG, +173556) ;
Upstream sequence
tagtaaaaggaaacaaccaatcaaaatttatcatgaacacatatgtgaaatttttaagtaaaattgcaacaaatgaatccagcaatatattaaagaaaga
Downstream sequence
gtgacatgaaagaaaaaaggctatcttagtctgttttctgttacctgaattccataaactgagtaatttataaagaaaataaatgtatttatttcttaca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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