VISDB Viral Integration Site DataBase

VIS ID

TVIS10008586

Fusion event

HBV-PRKG1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|large S protein|

Start

2985

Orient

-

Integrated sequence

TTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACA| |AGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGC

Chromosome

chr10

Cytoband

q21.1

Reference genome

Start

End

53089051/51329291 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-20a-5p ; hsa-mir-218-5p ; hsa-mir-3591-5p ; hsa-mir-1273e ; hsa-mir-921 ; hsa-mir-3606-5p

Nearest miRNA

hsa-mir-1265/Upstream/29636; hsa-mir-107/Downstream/3278583;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/254299, chr10-CpG: 40/Downstream/370200

Upstream sequence

tttttggctttacatttaagtatttaaatcatttttagtttatttttgtatatgatgtgagataagggtctaatttcattcttctacatgtggatattca

Downstream sequence

gtttcccctgcaccatttattgaagagaacgcccctttgcccttatatactcttggtgcctttgtcataaatcagttggctgtaaatgtggagatttatt