Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008589
Fusion event
HBV-TCTN1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2511
Orient
+
Integrated sequence
GCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACC| |TGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTT
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
End
111056000/110618195 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7i/Upstream/784759; hsa-mir-1178/Downstream/685947;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/3850, chr12-CpG: 58/Downstream/70611
Upstream sequence
ggagtctcactctgtcatccaggctggagtgcagtggtgtgatctcagtttactgcaacctctgccttctgggttgaaacgattctcctgcctcagcctc
Downstream sequence
cctgagtagctgggattacaggcgcccaccaccatacctggctaatttttgaattttttttttgagatggagtctcgctctgtcgcccaggctggaatgc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.