Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008593
Fusion event
HBV-LRRK1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2511
Orient
+
Integrated sequence
GCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACC| |TGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTT
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
End
101496792/100956587 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/2172085; hsa-mir-1302-10/Downstream/1003872;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/36569, chr15-CpG: 116/Downstream/16453
Upstream sequence
ctctgtcacccccaggctggagggctggagtgcagtggcacgatcttggctcactgcagcctccacctcccgggttcaagcaactctctgcctcagcctc
Downstream sequence
ctgagtagctgggattacaggcgcccacaaccacgcctggctaatttttgtgtttttagtagagacagggtttcaccatcttgaccaggctggtcttgaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.