VISDB Viral Integration Site DataBase

VIS ID

TVIS10008595

Fusion event

HBV-SIN3A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2511

Orient

+

Integrated sequence

GCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACC| |TGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTT

Chromosome

chr15

Cytoband

q24.2

Reference genome

Start

End

75726887/75434546 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-455-3p ; hsa-mir-93-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-218-5p ; hsa-mir-210-3p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-6796-5p ; hsa-mir-6759-5p ; hsa-mir-4322 ; hsa-mir-4296 ; hsa-mir-4265 ; hsa-mir-4668-5p ; hsa-mir-4267 ; hsa-mir-4762-5p ; hsa-mir-5586-5p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-548c-3p ; hsa-mir-1343-5p ; hsa-mir-149-3p ; hsa-mir-3150a-3p ; hsa-mir-3151-5p ; hsa-mir-3175 ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4519 ; hsa-mir-4728-5p ; hsa-mir-491-5p ; hsa-mir-5190 ; hsa-mir-591 ; hsa-mir-6081 ; hsa-mir-6731-5p ; hsa-mir-6742-5p ; hsa-mir-6763-5p ; hsa-mir-6785-5p ; hsa-mir-6825-5p ; hsa-mir-6856-5p ; hsa-mir-6883-5p ; hsa-mir-8085 ; hsa-mir-939-5p

Nearest miRNA

hsa-mir-10393/Upstream/80861; hsa-mir-11181/Downstream/327669;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/65827, chr15-CpG: 401/Downstream/16194

Upstream sequence

caagaccagaccggccaacatggtgaaaccctccctctactaaaaatacaaaaattagccgggtgtggttgtgggcgcctgtaatcccagctactcagga

Downstream sequence

ggctgaggcacgagaatcacttgaacctgggaggtggaggttgcagtgagccgaaatcgcgccactgcactccagcctgggcaatagagtggaactgtct