VISDB Viral Integration Site DataBase

VIS ID

TVIS10008606

Fusion event

HBV-ZNF566 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2511

Orient

+

Integrated sequence

GCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACC| |TGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTT

Chromosome

chr19

Cytoband

q13.12

Reference genome

Start

End

36967104/36476202 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-5186 ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-485-5p ; hsa-mir-1321 ; hsa-mir-3162-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-6884-5p ; hsa-mir-331-5p ; hsa-mir-202-3p ; hsa-mir-361-3p ; hsa-mir-330-3p ; hsa-mir-4678 ; hsa-mir-944 ; hsa-mir-4500 ; hsa-mir-4422 ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-mir-98-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-4477a ; hsa-mir-877-5p ; hsa-mir-520g-5p ; hsa-mir-126-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-323a-3p ; hsa-mir-33a-3p ; hsa-mir-3662 ; hsa-mir-218-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-636 ; hsa-mir-198 ; hsa-mir-6878-5p ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-6760-5p ; hsa-mir-576-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-20a-3p ; hsa-mir-4772-3p ; hsa-mir-1976 ; hsa-mir-660-3p ; hsa-mir-1306-5p ; hsa-mir-4695-3p ; hsa-mir-6787-3p ; hsa-mir-1304-3p ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-6736-3p ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-615-3p ; hsa-mir-3614-3p ; hsa-mir-1273g-3p ; hsa-mir-6809-3p ; hsa-mir-874-3p ; hsa-mir-3157-3p ; hsa-mir-7703 ; hsa-mir-4753-3p ; hsa-mir-4290 ; hsa-mir-4793-3p ; hsa-mir-6777-3p ; hsa-mir-483-3p ; hsa-mir-548av-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-25-5p ; hsa-mir-6087 ; hsa-mir-1247-3p ; hsa-mir-8057 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-665 ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-1827 ; hsa-mir-4635 ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-890 ; hsa-mir-216b-5p

Nearest miRNA

hsa-mir-10395/Upstream/1130575; hsa-let-7e/Downstream/2933421;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/54223, chr19-CpG: 44/Downstream/13086

Upstream sequence

cgaggccagcctggacaacatggcaaaaactcatctctactaaaaatacaaaaattagctgggtgtggttgtgggcgcctgtaatcccagctactcagga

Downstream sequence

ggctgaagtaggagaatcacttgaaccctggaggcagaggttgcagtaagccaagattgtgccactgtactccagcctagaagacagagcgagactccat