Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008608
Fusion event
HBV-SCTR integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2511
Orient
+
Integrated sequence
GCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACC| |TGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTT
Host Sequence
Chromosome
chr2
Cytoband
q14.2
Reference genome
End
120249210/119491634 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/5770266; hsa-mir-10b/Downstream/7931903;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/58902, chr2-CpG: 66/Downstream/32451
Upstream sequence
gagtttcactcttgttgcccaggctggagtgcaatggtgcgatcttggctcactgcaacctcagcctcctgggttcaagcgatcctcctgcctcagcctc
Downstream sequence
ctgagtagctgggattacaggcgcccacaaccacacccggctaattttgtatttttagtagagacagggtttcaccttgttggccaggctggtctcaaac
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.