Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008611
Fusion event
HBV-U2AF1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2511
Orient
+
Integrated sequence
GCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACC| |TGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTT
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
Start
End
44516909/43096799 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7c/Upstream/145785; hsa-mir-6070/Downstream/513088;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1349, chr21-CpG: 96/Downstream/10254
Upstream sequence
cggagtctcactctgtcgcccaggctggagtgcggtggcgcaatctcggctcactgcaacctccgcttcctgggctcatgcgattctctgcctcagcctc
Downstream sequence
ctgagtagctgggattacaggcgcccacaaccacgcccggctaatttttgtatttttaatagagatggggtttcaccatcttggccaggctagtcttgaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.