VISDB Viral Integration Site DataBase

VIS ID

TVIS10008612

Fusion event

HBV-CECR2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1078

Orient

-

Integrated sequence

ATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCA| |ATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGC

Chromosome

chr22

Cytoband

q11.21

Reference genome

Start

End

17921108/17442064 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1296-5p ; hsa-mir-484 ; hsa-mir-151a-3p ; hsa-mir-29b-3p ; hsa-mir-6880-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-6081 ; hsa-mir-6716-5p ; hsa-mir-3665 ; hsa-mir-3160-3p ; hsa-mir-125a-3p ; hsa-mir-6782-5p ; hsa-mir-3936 ; hsa-mir-4271 ; hsa-mir-3978 ; hsa-mir-877-5p ; hsa-mir-766-5p ; hsa-mir-1253 ; hsa-mir-520g-5p ; hsa-mir-3614-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-890 ; hsa-mir-4311 ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-520a-3p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-302e ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-520e

Nearest miRNA

hsa-let-7a-3/Downstream/322116;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/22824, chr22-CpG: 17/Downstream/139110

Nearby gene

CECR3(-173485) ; CECR2(+35520) ;

Upstream sequence

TTCTGAACATATTTCTCTGCAGGAAGCGGGTGGCAGACCTGTTGACTTCATTTTCATTGACCATCTTCTACTAGAATCAAACTCTGGTCTCTTTGAAATT

Downstream sequence

ATACAAAGTTGGGAAGCTGTTTACATTATCAACAGCTTTACCTATTTTGAATTCAGAAGAAGATTCAAGGTGGGAAAGACAGAAAAAACCGCAAAACAAG