Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008627
Fusion event
HBV-RANBP17 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|Polymerase|
Start
2420
Orient
-
Integrated sequence
TATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCG| |CAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAA
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
End
170630378/171203374 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10397/Upstream/1174808; hsa-mir-10523/Downstream/183282;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/340731, chr5-CpG: 417/Downstream/104791
Upstream sequence
AGGCGCGTAGACGCGGCTGGGGACGAACCCGAGGACGCATTGCTCCCTGGACGGGCACGCGGGACCTCCCGGAGTGCCTCCCTGCAACACTTCCCCGCGA
Downstream sequence
TCTCTTTAGTGTTGTTTGTGTATCCATGTAGATTATTGCAGTATTATCTGCTGCTTTGAGATAAAAGATATTGTTTGAGCATAAGAAATCTATTTCTTAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.