Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008628
Fusion event
HBV-THEMIS integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
421
Orient
+
Integrated sequence
CCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGC| |TATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCG
Host Sequence
Chromosome
chr6
Cytoband
q22.33
Reference genome
End
128169222/127848077 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/1363364; hsa-mir-1202/Downstream/3944095;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/331516, chr6-CpG: 173/Downstream/670936
Upstream sequence
agccgagattttgccactgcactccatcctgggctacagagccagacaccgtcataaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaGTTGCATGGT
Downstream sequence
ccccacaacaggccccggtgtgtgtgtgatgttccccttcctgtgtccatgtgttctcattgttcaattcccacctatgaatgagaacatgcggtgtttg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.