Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008634
Fusion event
HBV-PEX1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
807
Orient
-
Integrated sequence
AGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCA| |ATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTC
Host Sequence
Chromosome
chr7
Cytoband
q21.2
Reference genome
Start
End
92156773/92527459 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10525/Upstream/323361; hsa-mir-10399/Downstream/955301;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/79682, chr7-CpG: 90/Downstream/714
Upstream sequence
tgattcgcccgcctggacctcccaaagtgctgggattacaggcacgagccaccgcacctggctgttagctgtaattttctattaacttttactgatggac
Downstream sequence
GTGGACCAAAAATATCTTCCCCTAGGTATGGGGAAGTAACTCAAGTGGAAAGAAGGGATGCTTGAAATTATTGCAAACTCTATTCATTGCATAGATTAGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.