Basic Information
VIS ID
TVIS10008661
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2621
Orient
+
Integrated sequence
CCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAA| |GAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGT
Host Sequence
Chromosome
chr1
Cytoband
q21.2
Reference genome
End
145080522/148803839 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/415476; hsa-mir-1182/Downstream/1688506;
Nearby gene
PDE4DIP(-4336) ; SEC22B(+15885) ;
Upstream sequence
tcgagaccagcctgaccaacatggtgaaatccccgtctctactaaaaatacaaaaattagctgggcgtggtggcatgcacctgtaatcccagctactcag
Downstream sequence
gaagctgaagcaggataattgcttaaatctgggaggcagatgttgcagtgagccaagatcacaccactgcattccagcatgggcaacagacagagactct
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate