Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008662
Fusion event
HBV-CTSK integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1828
Orient
+
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
End
150767899/150795423 (Hg38)
Orient
+
Location type
downstream
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/243409; hsa-mir-1182/Downstream/750373;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/165698, chr1-CpG: 21/Downstream/130720
Upstream sequence
tacacccttaattctattccattgatctgtatgccttgactactattggtttgaagttaagttttgaaattgagaagtgcaagtcctccaactttgttct
Downstream sequence
ttttcaaggttgttttggctattctgaagcccttgaatgtccatatgaatcttagagccagcttgccaatttctgcaagaaagccagctgagattttaat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.