Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008663
Fusion event
HBV-CTSK integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1823
Orient
-
Integrated sequence
TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
End
150767911/150795435 (Hg38)
Orient
-
Location type
downstream
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-101-1/Upstream/243421; hsa-mir-1182/Downstream/750361;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/165710, chr1-CpG: 21/Downstream/130708
Upstream sequence
tctattccattgatctgtatgccttgactactattggtttgaagttaagttttgaaattgagaagtgcaagtcctccaactttgttctttttcaaggttg
Downstream sequence
ttttggctattctgaagcccttgaatgtccatatgaatcttagagccagcttgccaatttctgcaagaaagccagctgagattttaatacaaattgtgtt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.