Basic Information
VIS ID
TVIS10008666
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
315
Orient
-
Integrated sequence
CTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCG| |CAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCC
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
End
195964904/195995774 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/2859191; hsa-mir-1182/Downstream/586639;
Nearby gene
KCNT2(+230009) ;
Upstream sequence
CTATCTTTTTTTACAGTTCTGTTTTTTTATATTTGAATATGTAAATATATTGAGTGAAAATGCAACTCTAAAACTTCAGTATACATTGTAAAAATAATTT
Downstream sequence
CCAGTAATGCCTGTCTTTGAGACTCCTCTAAAACTACTTTCTCATGTATTATAATGCAACAATCAAATGCTTGTTACATTTTCCACATATATCTTGCTGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate