Fusion event
HBV-chr1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
CTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCG| |CAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCC
End
195964904/195995774 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/2859191; hsa-mir-1182/Downstream/586639;
Upstream sequence
CTATCTTTTTTTACAGTTCTGTTTTTTTATATTTGAATATGTAAATATATTGAGTGAAAATGCAACTCTAAAACTTCAGTATACATTGTAAAAATAATTT
Downstream sequence
CCAGTAATGCCTGTCTTTGAGACTCCTCTAAAACTACTTTCTCATGTATTATAATGCAACAATCAAATGCTTGTTACATTTTCCACATATATCTTGCTGT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.