KCNT2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10008668
Fusion event
HBV-KCNT2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1769
Orient
-
Integrated sequence
GGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCT| |TTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAA
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
End
196414208/196445078 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/3308495; hsa-mir-1182/Downstream/137335;
Upstream sequence
CAGTCTAAAAGGATTTTCTAAGTTGTGAGCCCTTTATTCTCTACAACCTACTTTTCTTTTTGCTTAAATTTATTTTACTTATCTCATTCAGCCCTTAAAA
Downstream sequence
GTAAAGTGTATATCCAAGAAATAATATAGAAATATTAGCTTACACACTATTTCCATTATATGTTTAAAGATATGTTCACAGATTTGATAAAAATAAAATA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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